Objective: Chemotherapy is one of the important adjuvant methods for the treatment of glioblastoma (GBM), and chemotherapy resistance is a clinical problem that neurooncologists need to solve urgently.It is reported that Saikosaponin D (SSD), Garment Steamer an active component of Bupleurum chinense, had various of antitumor activities and could al
The management of subjective quality of life by short-stay hospital patients: An exploratory study
Abstract Background This study tested the homeostatic model of subjective quality of life in a group of 47 short stay patients as they progressed Beet through the stages of hospitalization for surgery.Method Participants completed a questionnaire measuring subjective quality of life, positive and negative affect, self-esteem, optimism and cognitive
Modeling of spontaneous emission in presence of cylindrical nanoobjects: the scattering matrix approach
We propose a method of analysis of spontaneous emission of a quantum emitter (an atom, a luminescence center, a ORG COFFEE SUBSTITUTE quantum dot) inside or in vicinity of a cylinder.At the focus of our method are analytical expressions for the scattering matrix of the cylindrical nanoobject.We propose the approach to electromagnetic field quantiza
Anti-fibrotic activity of a rho-kinase inhibitor restores outflow function and intraocular pressure homeostasis
Glucocorticoids are widely used as an ophthalmic medication.A common, sight-threatening adverse event of glucocorticoid usage is ocular Ribbed Turtleneck hypertension, caused by dysfunction of the conventional outflow pathway.We report that netarsudil, a rho-kinase inhibitor, decreased glucocorticoid-induced ocular hypertension in patients whose in
The tardigrade protein CAHS D interacts with, but does not retain, water in hydrated and desiccated systems
Abstract Tardigrades are a group of microscopic animals renowned for their ability to survive near complete desiccation.A family of proteins, unique to tardigrades, called Cytoplasmic Abundant Heat Soluble (CAHS) proteins are necessary to mediate robust desiccation tolerance in these animals.However, the mechanism(s) by which CAHS proteins help to